This signal is recorded continuously and in real time. For each sample there is a reference that is on a parallel heat flow sensor. During the time that the heat flow is monitored, any temperature fluctuations entering the instrument will influence both the sample and the reference sensors equally. This architecture allows a very accurate determination of heat that is produced or consumed by the sample alone while other non-sample heat disturbances are efficiently factored out. Calorimetry requires little or no sample pretreatment, liquid-liquid or solid-liquid systems can be analyzed.

Reaction (mixing) calorimetry measures the heat released from a chemical reaction or physical process under process-like conditions and provides the fundamentals of the thermochemistry and kinetics of a reaction. Calorimetric information is crucial when determining how chemical reactions can be transferred safely from lab to plant. The user can investigate the reaction under realistic conditions in a small laboratory reactor. Along with the chemical development workflow, reaction calorimetry provides the information needed for each of the individual steps and is subsequently converted into information to evaluate the risk, scalability and criticality of a process.

Method allows comprehensively and precisely study the thermal processes of mixing and reactions, even in samples of large volume: high sensitivity ensures accurate measurement of heat or heat absorption, proper conduct measurements of the total heat flow, the simultaneous ability to control pressure.