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Scientific Reports 7, Article number: 41991, Pages 1-10

E.G. Vlakh, E.V. Grachova, D.D. Zhukovsky, A.V. Hubina, J.R. Shakirova, A.S. Mikhailova, V.V. Sharoyko, S.P. Tunik, T.B. Tennikova

Self-assemble nanoparticles based on polypeptides containing C-terminal luminescent Pt-cysteine complex

Scientific Reports 7, Article number: 41991, Pages 1-10

DOI: 10.1038/srep41991

The growing attention to the luminescent nanocarriers is strongly stimulated by their potential application as drug delivery systems and by the necessity to monitor their distribution in cells and tissues. In this communication we report on the synthesis of amphiphilic polypeptides bearing C-terminal phosphorescent label together with preparation of nanoparticles using the polypeptides obtained. The approach suggested is based on a unique and highly technological process where the new phosphorescent Pt-cysteine complex serves as initiator of the ring-opening polymerization of α-amino acid N-carboxyanhydrides to obtain the polypeptides bearing intact the platinum chromophore covalently bound to the polymer chain. It was established that the luminescent label retains unchanged its emission characteristics not only in the polypeptides but also in more complicated nanoaggregates such as the polymer derived amphiphilic block-copolymers and self-assembled nanoparticles. The phosphorescent nanoparticles display no cytotoxicity and hemolytic activity in the tested range of concentrations and easily internalize into living cells that makes possible in vivo cell visualization, including prospective application in time resolved imaging and drug delivery monitoring.

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Journal of Non-Crystalline Solids 457 (2017) 164–168

D.V. Pan'kin, М.V. Sukhanov, Yu.S. Tver'yanovich, М.F. Churbanov

«Investigation of structure of GeS_1.35 glasses with the use of isotopically enriched germanium and Raman scattering spectroscopy»

Journal of Non-Crystalline Solids 457 (2017) 164–168

DOI: 10.1016/j.jnoncrysol.2016.11.038

The samples of GeS_1.35 glasses were synthesized with germanium and sulfur of natural isotopic composition and with isotopically enriched germanium (⁷²Ge, ⁷⁴Ge, ⁷⁶Ge). The glasses were investigated by the method of Raman scattering spectroscopy (RSS). It was shown that GeS_4/2 tetrahedrons and structural units containing Ge\\Ge homobonds are present in glasses. The quantum-mechanical calculation of the frequency of fundamental vibrational modes in glass network was carried out. Their dependencies on the atomic mass of germanium were used for identification of bands in RS (Raman scattering) spectra.

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Inorganica Chimica Acta Volume 455, Part 1, 30 January 2017, Pages 9–14

Dmitrii S. Bolotin, Mikhail V. Il’in, Ilya E. Kolesnikov, Vitaliy V. Suslonov, Yuri Novozhilov, Oksana Ronzhina, Mikhail Krasavin, Vadim P. Boyarskiy, Renier Koen, Andreas Roodt

Fluorescent (pyrazolyl acetoxime)ZnII complexes: synthetic, structural, and photophysical studies

Inorganica Chimica Acta Volume 455, Part 1, 30 January 2017, Pages 9–14

DOI: 10.1016/j.ica.2016.10.008

Treatment of pyrazolyl acetoximes p-RC₆H₄{CN(H)NCCH}CH₂C(Me)=NOH (R = OMe, H, F, Cl, CN, NO₂) with 1 equiv of ZnCl₂ leads to the complexes [ZnCl₂(p-RC₆H₄{CN(H)NCCH}CH₂C(Me)=NOH)] (81–91%). These species exhibit fluorescence at room temperature with emission maxima in the region 460–509 nm and biexponential relaxation with τ₁ = 4.63–8.64 ns and τ₂ = 0.482–0.955 ns, respectively. The zinc complexes were characterized by elemental analyses (C, H, N), HRESI-MS, FTIR, ¹H and ¹³C{¹H} NMR, and CP-MAS TOSS ¹³C{¹H} NMR. In addition, two zinc complexes and one pyrazolyl acetoxime were studied by single-crystal X-ray diffraction.

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Dalton Transactions Issue 8, Pages 2516-2523

J.R. Shakirova, E.V. Grachova, V.V. Sizov, G.L. Starova, I.O. Koshevoy, A.S. Melnikov, M.C. Gimeno, A. Laguna, and S.P. Tunik

Polynuclear cage-like Au(I) phosphane complexes based on S²⁻ template: observation of multiple luminescence in coordinated polyaromatic systems

Dalton Transactions Issue 8, Pages 2516-2523

DOI: 10.1039/C6DT04126D

A rational approach to the synthesis of cage-like compounds has been realized to build a new family of sulfido-phosphane Au(I) polynuclear complexes. Ditopic phosphane ligands with an extended aromatic system were used to obtain cage compounds with a clearly determined geometry. Au(I) complexes have been fully characterised in solution using spectroscopy methods, and DFT optimisation of the molecular structure gives additional arguments in favour of the suggested structural patterns. All complexes obtained are luminescent in solution and in the solid state, and display multiple emissions with an unusual combination of two phosphorescence bands and one fluorescence band. DFT calculations show that multiple emissions were mainly determined by ¹IL and metal perturbed ³IL transitions. The ratio of singlet and triplet emission components depends on the distance between the ligand chromophoric centre and Au(I).

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Optical and Quantum Electronics Volume 49, No.1, January 2017, Article 40, Pages 1-9

E. I. Ageev, D. V. Potorochin, D. V. Sachenko, G. V. Odintsova

Generation of web-like structures and nanoparticles by femtosecond laser ablation of silicon target in ambient air

Optical and Quantum Electronics Volume 49, No.1, January 2017, Article 40, Pages 1-9

DOI: 10.1007/s11082-016-0875-5

Silicon nanoparticles were produced by femtosecond laser ablation in ambient air. Obtained samples were studied using dark-field optical microscopy, scanning electron microscopy and Raman-scattering spectroscopy. Two groups of structures can be found: (1) branched amorphous structures with a minimum element size of about 10 nm and incorporations of nanocrystals (0.6–6.6 nm from Raman scattering analysis); (2) larger crystal particles with smooth surface and a typical size of 50–200 nm that provide directional visible light scattering (at dark-field optical microscopy observations). An influence of environment on resulting phase composition of silicon nanoparticles was investigated by numerical evaluation of nanoparticle’s cooling rate. The calculation shows that cooling in ambient air ensures cooling rate sufficient for crystallization.