V.A. Rassadin, E. Nicolas, Y. Six
«Ti(OiPr)4/nBuLi: an attractive reagent system for [2+2+2] cyclotrimerisation reactions»
Chem. Commun. 2014, Advance Article
DOI: 10.1039/C4CC02698E
A convenient method for the [2+2+2] cyclotrimerisation of alkynes using Ti(OiPr)4/nBuLi is presented. Homotrimerisation of arylacetylenes proceeds within minutes with excellent regioselectivity. Moreover, the intermolecular construction of ABB heterotrimers can be achieved selectively from two different alkynes with similar electronic properties. The method is also suitable for the synthesis of pyridines.
16 и 18 июня прошла вторая часть семинара G-RISC “NMR as interdisciplinary tool for the study of non-covalent interactions”.
Были сделаны следующие доклады:
- Regina Islamova “Transition Metal-Catalyzed polymerisation: NMR and EPR study”;
- Roman Yakovenko “NMR study of protonation of carbonyl compounds (fluorinated enones and furanes) in Brønsted superacids”;
- Konstantin Luzyanin “Combining NMR and MS tools for study of nano clusters in solution”;
- Kirill Kulish “Zinc(II)-Mediated Generation of 5-amino-1,2,4-oxadiazoles from amidoximes and cyan amides”
Опубликован отчёт о деятельности ресурсного центра ФМИП за первую половину 2014 года - pdf-файл.
J. Malinina, T.Q. Tran, A.V. Stepakov, V.V. Gurzhiy, G.L. Starova, R.R. Kostikov, A.P. Molchanov
«[3+2] Cycloaddition reactions of arylallenes with C-(N-arylcarbamoyl)- and C,C-bis(methoxycarbonyl)nitrones and subsequent rearrangements»
Tetrahedron Lett. 2014, 55, 3663-3666
DOI: 10.1016/j.tetlet.2014.04.107
The first example of 1,3-dipolar cycloaddition reactions of nitrones with arylallenes is described. C-Carbamoylnitrones react with the C1single bondC2 double bond of arylallenes affording the corresponding 4-methyleneisoxazolidines in good yields. N-Aryl-C,C-bis(methoxycarbonyl)nitrones usually gave rearranged products: mixtures of 4,5-dihydro-4-oxo-1H-benzo[b]azepine-2,2(3H)dicarboxylates and 4-oxo-1,5-diarylpyrrolidine-2,2-dicarboxylates.
10 июня в РЦ "Оптические и лазерные методы исследования вещества" состоялась профориентационная экскурсия для учащихся Санкт-Петербургского кадетского корпуса.
