Saint-Petersburg State University
FSBSI “The Research Institute of Obstetrics, Gynecology and Reproductology
named after D.O.Ott”
International Scientific Conference of Saint-Petersburg State University Research Park
Translational biomedicine: exploring modern techniques of interdisciplinary research in implication to applied medicine
Saint-Petersburg
10-12 November 2015
PROGRAMME
Organizers of the Conference:
Federal State Budget Educational Institution of Higher Education “Saint-Petersburg State University”
Russia, 199034, Saint-Petersburg,
7-9, Universitetskaya nab.
Phone/Fax: +7 (812) 328-20-00 E-mail:
Co-organizers of the Conference:
Russian Academy of Sciences
FSBSI “The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O.Ott”
Russia, 199034, Saint-Petersburg,
3, Mendeleyevskaya line
Phone: +7 (812) 325-32-20
Fax: +7 (812) 328-23-61 e-mail:
November 10th 2015, Tuesday (Assembly Hall, SPbSU, 7-9, Universitetskaya nab.)
08.00-09.30 REGISTRATION
10.00-10.30 OPENING CEREMONY
Chairmen: Vice-rector for research of SPbSU prof. S.P. Tunik, acad. of RAS E.K. Ailamazyan, corresponding member of RAS V.S. Baranov, acad. of RAS S.G. Inge-Vechtomov, director of the Institute of Translational Biomedicine of SPBSU prof. R.R. Gainetdinov, director of FSBI “St. Petersburg Versatile Center” of Russian Ministry of Health M.D. U.N. Fedotov
Opening speech
- Vice-rector for research of SPbSU prof. Sergei Pavlovich Tunik
- Prof. of SPbSU, director of FSBSI “The Research Institute of Obstetrics, Gynecology and - Reproductology named after D.O.Ott”, acad. of RAS, Edward Karpovich Ailamazyan
- Head of the Department of genetics and biotechnology of SPbSU, acad. of RAS Sergei Georgievich Inge Vechtomov
10.30-12.00FIRST PLENARY SESSION
«GENETICS AS THE BASIS OF TRANSLATIONAL BIOMEDICINE»
Joint meeting with Scientific Practical Conference “New opportunities of prenatal diagnostics and genetic testing in the age of translational medicine”
Co-chairmen: acad. of RAS E.K. Ailamazyan, acad. of RAS V.P.Puzyrev
- V.S. Baranov (Saint-Petersburg), From predictive through translational to exact medicine. The evolution of concepts, 20 min.
- V.P. Puzirev (Tomsk), Genetics of human comorbidity: sources, current state, perspectives, 20 min.
- Thomas Liehr (Jena, Germany), Small supernumerary marker chromosomes (sSMC): the genotype-phenotype correlation and the problem of discontinuity, 20 min.
- N.B. Rubtsov (Novosibirsk), Problems of modern cytogenetic diagnostics: Woe from Wit, 20 min.
12.00-12.20 Coffee break
12.20-14.00 FIRST PLENARY SESSION (continuation)
«MAIN ISSUES OF TRANSLATION OF GENETIC THEORETICAL KNOLEDGE INTO PRACTICE»
Joint meeting with Scientific Practical Conference “New opportunities of prenatal diagnostics and genetic testing in the age of translational medicine”
Co-chairmen: corresponding member of RAS V.S. Baranov, M.D. V.L.Izhevskaya
- E.K. Khusnutdinova (Ufa), Genomics of monogenic diseases, 20 min.
- A.V. Poljakov (Moscow), Genotyping of phenylketonuria patients for further treatment with kulan medicine, 20 min.
- V.L. Izhevskaya (Moscow), Old and new ethical problems of genetic testing in the light of new technologies of genome research, 20 min.
- T.V. Kharchenko (Saint-Petersburg), Problems of education of physicians-geneticists and laboratory genetic diagnostics specialists, 20 min.
- E.B. Prokhorchuk (Moscow), Reading, understanding and editing of genetic texts as instruments of translational medicine, 20 min.
14.00-15.00 Lunch
15.00-16.45 SYMPOSIUM
«NEW OPPORTUNITIES IN BIOMEDECINE»
Co-chairmen: PhD S.V.Mikushev, PhD P.A. Zykin, PhD A.F. Saifitdinova
Reports of young scientists
- M.S. Barkovskaya (Novosibirsk), Development of the software for the telomere length assessment of human individual chromosomes using Q-FISH technique, 15 min.
- D.S. Poljakov (Saint-Petersburg), Biotinylation of the plasmid coding strand doesn't disrupt the translation of the containing in it target gene, 15 min.
- A.A. Nizhnikov (Saint-Petersburg), Proteomic screening of the amyloid-forming proteins in Escherichia coli, 15 min.
- E.G. Bogomolova (Saint-Petersburg), Immunogen generating on a basis the capsid proteins of the human rotavirus A, 15min.
- R.K. Ovchinnikov (Chernogolovka), Modeling of the neurodegenerative process in transgenic mice expressing an aberrant form of human FUS protein, 15 min.
16.45-17.00 Coffee break
17.00-18.00 Poster session for young scientists
15.00-18.00 Solemn ceremony dedicated to the anniversary of the corresponding member of RAS V.S. Baranov (Assembly Hall of FSBSI “RI of OGR named after D.O.Ott”
November 11th 2015, Wednesday
09.00-11.00 SYMPOSIUM (Lecture-room №1, FSBSI “RI of OGR named after D.O.Ott”, 3, Mendeleyevskaya line)
«NEW METHODS IN PRENATAL DIAGNOSTICS»
Joint meeting with Scientific Practical Conference “New opportunities of prenatal diagnostics and genetic testing in the age of translational medicine”
Co-chairmen: corresponding member of RAS V.S. Baranov, prof. T.V. Kuznetsova
- L.A. Zhuchenko (Moscow), Audit of early prenatal screening 2015 (EPS-15), 30 min.
- E.B. Prokhorchuk (Moscow), State and possibilities of non-invasive prenatal diagnostics (NIPD) in Russia, 20 min.
- V.A. Gnetetskaya (Moscow), Prenatal diagnostics in the age of molecular technologies, 20 min.
- T.K. Kasheeva (Saint-Petersburg), Here is the question: NIPT or not NIPT?, 20 min.
Comments, discussion, 20 min.
V.S. Baranov, Concluding remarks, 5 min.
10.00-18.00 Workshops
Workshops
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Workshop №1 BioLine: «Flow cytometry technique for solving clinical and scientific problems»
Venue: SPbSU, RRC for molecular and cell technologies, 7-9, Universitetskaya nab., building «R», room 401 Class starts at 10.00 Duration: 3 hours
Workshop is held by: Igor Reshetnikov, flow cytometry specialist, “BioLine”
Optimal number of participants is up to 20.
Executive: Kseniia Fedoseeva, Deputy director of RRC for molecular and cell technologies, phone: 328-96-96 |
Workshop №2 «Electron microscopy: new possibilities in sample preparation robotics»
Venue: SPbSU, RRC for molecular and cell technologies, 7-9, Universitetskaya nab., building «R», room 304 Class starts at 10.00 Duration: 2 -3 hours
Workshop is held by: PhD Alexandra Ivanova, specialist of RRC for molecular and cell technologies, SPbSU
Optimal number of participants is up to 10.
Executive: Kseniia Fedoseeva, Deputy director of RRC for molecular and cell technologies, phone: 328-96-96 |
Workshop №3 Merk «RNA detection in live cells using Smart Flare technology»
Venue: SPbSU, RRC for molecular and cell technologies, 7-9, Universitetskaya nab., building «R», rooms 307, 301 Class starts at 10.00 Duration: 3 hours
Workshop is held by: Marina Prokhorova, Application specialist, Merk LLC
Optimal number of participants is up to 15.
Executive: Kseniia Fedoseeva, Deputy director of RRC for molecular and cell technologies, phone: 328-96-96 |
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Workshop №4: «The possibility of using metabolomic approaches in the clinical practice»
Venue: SPbSU, RRC for molecular and cell technologies, 7-9, Universitetskaya nab., building «R», rooms 108, 401
Class starts at 15.00 Duration: 3 hours
Workshop is held by: PhD Alexei Shavarda, specialist of RRC for molecular and cell technologies, SPbSU
Optimal number of participants is up to 10
Executive: Kseniia Fedoseeva, Deputy director of RRC for molecular and cell technologies, phone: 328-96-96 |
Workshop №5 BioLine: «Single cell sorting for the following molecular analysis and cultivation»
Venue: SPbSU, RRC for molecular and cell technologies, 7-9, Universitetskaya nab., building «R», rooms 401, 303
Class starts at 14.00 Duration: 4 hours
Workshop is held by: Nikolai Galaktionov, specialist of RRC for molecular and cell technologies, SPbSU; Tatiana Chudinova, specialist of RRC for molecular and cell technologies, SPbSU; and Ivan Diachkov, “BioLine”
Optimal number of participants is up to 10
Executive: Tatiana Chudinova, specialist of RRC for molecular and cell technologies, SPbSU, phone: 328-96-96 |
Workshop №6 «Modern microscopy techniques for biomedical research and cytogenetic diagnostics»
Venue: SPbSU, RC “Chromas Core Facility”, 2 Oranienbaumskoe shosse, building 5
Class starts at 11.00 and at 15.00 Duration: 3- 4 hours
Workshop is held by: PhD Alsu Saifitdinova, director of RC “Chromas Core Facility”, SPbSU
Optimal number of participants is up to 10. If necessary, the second group can be assembled starting at 15.00.
Executive: Alsu Saifitdinova, director of RC “Chromas Core Facility”, phone 450-73-11, cell phone +7(921)0987084 |
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Workshop №7 Quadros Bio: «Biobanking and sample preparation (biobank creation for different tasks)»
Venue: FSBSI “RI of OGR named after D.O.Ott”, 3, Mendeleyevskaya line, lecture-room №1
Class starts at 11 00 Duration: 1 hour 50 min
Workshop is held by: PhD Andrei Glotov, director of RC “Biobank Center”, senior researcher of Lab. of prenatal diagnostics; and Artem Muraviev, “Quadros Bio”
Optimal number of participants is up to 30.
Executive: Andrei Glotov, Director of RC “Biobank Center”, cell phone: +79213225380 |
Workshop №8 Helicon: «DNA extraction and creation of DNA libraries»
Venue: FSBSI “RI of OGR named after D.O.Ott”, 3, Mendeleyevskaya line, lecture-room №2
Class starts at 13 00 Duration: 1 hour 50 min
Workshop is held by: PhD Dmitrii Polev, leading specialist of RC “Biobank Center”, SPbSU
Optimal number of participants is up to 30.
Executive: Andrei Glotov, Director of RC “Biobank Center”, cell phone: +79213225380 |
Workshop № 9 Round table «Interpretation of NGS sequencing data for clinical diagnostics»
Venue: FSBSI “RI of OGR named after D.O.Ott”, 3, Mendeleyevskaya line, conference hall, lecture-room №1
Class starts at 15 00 Duration: 3 hours
Workshop is held by: PhD Andrei Glotov, director of RC “Biobank Center”, senior researcher of Lab. of prenatal diagnostics; and Vera Korneeva, technical support and training specialist, “Helicon”
Optimal number of participants is up to 30.
Executive: Andrei Glotov, Director of RC “Biobank Center”, cell phone: +79213225380 |
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Workshop №10 « Hamilton robotic solutions for scientific and applied researches»
Venue: FSBSI “RI of OGR named after D.O.Ott”, 3, Mendeleyevskaya line, lecture-room №2
Class starts at 13 00 Duration: 2 hours
Workshop is held by: Andrei Glotov, Director of RC “Biobank Center”, SPbSU, Ekaterina Selivanova, OOO “InterLabService”
Optimal number of participants is up to 20
Executive: Andrei Glotov, Director of RC “Biobank Center”, cell phone: +79213225380 |
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November 12th 2015, Thursday
08.30-10.45 SECOND PLENARY SESSION (University center, SPbSU, V.I., Birzhevaya Linia, 6, acad. Sakharov Square)
«GENOMICS, PROTEOMICS AND METABOLOMICS»
Co-chairmen: prof. R.R. Gainetdinov, prof. A.L. Lapidus
- R.R. Gainetdinov (Saint-Petersburg), Transgenic models of human diseases in translational biomedicine, 20 min.
- A.A. Rubel, U.O. Chernov (Saint-Petersburg), Amyloid biology, 15 min.
- A.L. Lapidus (Saint-Petersburg), Bioinformatics serving biomedicine, 20 min.
- Eystein S. Husebye (Norway), Monogenic causes of autoimmunity, 20 min.
- E.D. Ponomarev (Hong Kong, China), Role of platelets in regulation of an inflammation in the central nervous system: potential applications for diagnostics and treatment of multiple sclerosis, 20 min.
- N.U. Isupova (Sain-Petersburg), Shimadzu analytic equipment for complex biomedical research, 15 min.
10.45-11.00 Coffee break
11.00-13.00 THIRD PLENARY SESSION (University center, SPbSU, V.I., Birzhevaya Linia, 6, acad. Sakharov Square)
«BIOBANKS AND POPULATIONAL GENOMICS»
Co-chairmen: MD A.M. Sarana, PhD A.S. Glotov
- A.M. Sarana (Saint-Petersburg), Role of large clinics in the organization of national Biobank, 25 min.
- A.S. Glotov (Saint-Petersburg), RC “Biobank Center” of SPbSU Research park – as the hub for organization of medical genetic research, 20 min.
- A.B. Maslennikov (Novosibirsk), Legal bases of genetic testing and legislation problems, 20 min.
- O.P. Balanovskyi (Moscow), Gene geography in medicine and forensic medical examination, 20 min.
- A.V. Karassev (Moscow), Advanced Automation Technologies in scientific research, 10 min.
11.00-13.00 SYMPOSIUM (Lecture-room №1, FSBSI “RI of OGR named after D.O.Ott”, 3, Mendeleyevskaya line)
«NEW APPROACHES AND TECHNIQUES IN TRANSLATIONAL BIOMEDICINE »
Co-chairmen: PhD P.A. Zykin, PhD K.V. Volkov
- M.V. Prokhorova (Moscow, Merck compony), Gene expression analysis in living cells on the example of monocytes and macrophages using the SmartFlare technology, 15 min.
- A.A. Aksenova (Saint-Petersburg), Instability of interstitial telomeric sequences, 15 min.
- A.D. Ephimova (Chernogolovka), The increase of glutamate secression in a cerebral cortex of new transgene model of a amyotrophic lateral sclerosis, 15 min.
- M.N. Sudalina (Saint-Petersburg), Research of the proapoptotic properties of synthetic kisspeptins in tumor cell culture of female reproductive system, 15 min.
- I.D. Klabukov (Moscow), Choice of biocompatible materials for tissue engineering in a reconstructive liver surgery, 15 min.
- A.U. Chernenkov (Saint-Petersburg), Genes of HSM family: DNA reparation and modifications in chromatin structure, 15 min.
13.00-14.00 Lunch
14.00-15.30 SYMPOSIUM (University center, SPbSU, V.I., Birzhevaya Linia, 6, acad. Sakharov Square)
«NON-INVASIVE AND PREIMPLANTATIONAL DIAGNOSTICS»
Co-chairmen: MD E.V. Komlichenko, PhD A.F. Saifitdinova
- F.Graedler, (USA, Illumina), New methods of genetic analysis in the field of reproductive health, 20 min.
- U.A. Loginova (Saint-Petersburg), Efficiency and long-term effects of preimplantational genetic diagnostics of gene and chromosome diseases, 20 min.
- A.V. Ivanov (Saint-Petersburg), Diagnostics of SNP gene factors of thrombophilia and folate cycle during in vitro fertilization (IVF) preparation, 15 min.
- P.A. Zykin (Saint-Petersburg), Early non-invasive diagnostic of socially important human neurologic diseases, 20 min.
- M.N. Peshkov (Moscow), Molecular genetic methods of diagnostics of prostate gland tissue neotransformation, 15 min.
- G.Shaidullina (Moscow, LECO Corporation), From the statistical analysis of mass-spectrum arrays of individual organic matters to metabolome and diagnostics, 15 min.
15.50-16.10 Coffee break
14.00-15.30 SYMPOSIUM (Lecture-room №1, FSBSI “RI of OGR named after D.O.Ott”, 3, Mendeleyevskaya line)
«NEW METHODS IN DIAGNOSTICS OF CHILDREN RARE DESEASES»
Joint meeting with Scientific Practical Conference “New opportunities of prenatal diagnostics and genetic testing in the age of translational medicine”
Co-chairmen: PhD A.S. Glotov, MD E.B. Bashnina
- A.V. Karpushkina (Moscow), Providing quality and availability of molecular and genetic research. “Alfa-Endo” programme, 15 min.
- O.S. Glotov (Saint-Petersburg), The analysis of exomes of patients with endocrine diseases. First results, 20 min.
- E.M. Orlova (Moscow), Rare hereditary forms of adrenal insufficiency, 15 min.
- Eystein S. Husebye (Norway), The autoimmune syndromes connected with the mutation in the autoimmune regulator gene, 20 min.
- K.V. Volkov (Saint-Petersburg), Perspectives of use of instrumental and intellectual base of the Reseach resource center for molecular and cell technologies for the benefit of applied medicine, 15 min.
- E.B. Bashnina (Saint-Petersburg), The significance of molecular and genetic diagnostics in clinical practice in children's endocrinology (analysis of clinical cases), 20 min.
15.50-16.20 Coffee break
16.20-18.00 FORTH PLENARY SESSION (University center, SPbSU, V.I., Birzhevaya Linia, 6, acad. Sakharov Square)
«PERSPECTIVES OF BIOMEDICINE DEVELOPMENT»
Co-chairmen: prof. S.P. Tunik, PhD S.V.Mikushev
- Rob Hastings (USA, Illumina), National Sequencing Projects to better diagnose, categorise and treat clinical conditions, 20 min.
- V.B. Bruekhin (Saint-Petersburg), “Russian Genome” project. Purposes and tasks, 20 min.
- V.I. Larionova (Saint-Petersburg), Metabolic and molecular bases of the personalized therapy choice in hereditary metabolic diseases, 20 min.
- A.P. Galkin (Saint-Petersburg), Identification of proteins forming pathological amyloid aggregations in the human senescent brain, 20 min.
- V.Korneeva (Moscow, Helicon company), Research and diagnostic on the basis of single cell analysis, 15 min.
18.00-18.30 Handing of awards and diplomas to the winners of a poster session.
Concluding remarks.
19.00 Gala dinner
