Confocal laser microscope LEICA TCS SPE – this is a point scanning confocal system with a spectral detector for fluorescence registering the spatial structure of living and fixed objects . As the light source are lasers with high intensity and the monochromaticity of the radiation. The system consists of four solid-state laser with a wavelength of 405 , 488 , 532, and 635 nm. Confocal microscopy is widely used in the fields of biology , medicine , biophysics, molecular and cellular biology . It allows you to explore the tissue at the cellular level in a state of physiological activity.